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Liver fluke infections 

Liver fluke infections
Chapter:
Liver fluke infections
Author(s):

David I. Grove

DOI:
10.1093/med/9780199204854.003.071102_update_001

Update:

Opisthorchiasis and clonorchiasis—tribendimidine is a potential new alternative anthelminthic.

Fascioliasis—artesunate for treatment.

Updated on 31 May 2012. The previous version of this content can be found here.
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date: 18 October 2017

Clonorchis (syn. Opisthorchis) sinensis is a fluke (flatworm) acquired by ingestion of undercooked freshwater fish in eastern Asia. Larvae in the duodenum enter the biliary tree through the sphincter of Oddi and mature. Most patients are asymptomatic, but there may be right upper abdominal discomfort, and infection can be complicated by bacterial cholangitis and there is an increased risk of cholangiocarcinoma. Diagnosis is suggested by finding eggs in faeces or in duodenal aspirates, but can only be confirmed by examination of adult flukes. Treatment is with praziquantel....

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