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Cystic hydatid disease (Echinococcus granulosus) 

Cystic hydatid disease (Echinococcus granulosus)

Chapter:
Cystic hydatid disease (Echinococcus granulosus)
Author(s):

Armando E. Gonzalez

, Pedro L. Moro

, and Hector H. Garcia

DOI:
10.1093/med/9780199204854.003.071001_update_001

Update:

Treatment—possible use of oxfendazole in humans.

Updated on 31 May 2012. The previous version of this content can be found here.
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date: 26 March 2017

Cystic hydatid disease, caused by Echinococcus granulosus, is a zoonotic disease principally transmitted between dogs and domestic livestock, particularly sheep. Humans are infected when they ingest tapeworm eggs, with disease occuring in most parts of the world where sheep are raised and dogs are used to herd livestock.

Clinical features, diagnosis, and treatment—the most common clinical manifestations are cysts in the liver (typically presenting with hepatomegaly) and/or lung (presenting with cough, haemoptysis, and dyspnoea). Diagnosis is usually made on the basis of serological tests in combination with imaging techniques. Treatment options include surgery, chemotherapy with anthelminthic agents, or—for liver cysts—PAIR (puncture–aspiration–injection–reaspiration).

Prevention—echinococcosis is a major public health problem in several countries. Control programmes have been aimed at educating dog owners to prevent their animals from having access to infected offal. Vaccines against sheep hydatidosis and the dog tapeworm stage are promising alternatives.

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