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Gnathostomiasis 

Gnathostomiasis
Chapter:
Gnathostomiasis
Author(s):

Valai Bussaratid

and Pravan Suntharasamai

DOI:
10.1093/med/9780199204854.003.070907_update_001

Update:

Diagnosis—two new serodiagnostic immunoblot tests have been developed.

Further reading—new references added.

Updated on 31 May 2012. The previous version of this content can be found here.
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date: 25 September 2017

Gnathostomiasis is an extraintestinal infection with larval or immature nematodes of the genus Gnathostoma (order Spirurida), the most common mode of human infection being consumption of undercooked freshwater fish. Clinical manifestations include recurrent cutaneous migratory swellings (common), creeping eruption (rare), and neurological deficits (occasional). Definitive diagnosis is by identification of the worm in surgical specimens; serological testing for antibody against gnathostoma antigen can confirm a presumptive diagnosis. Treatment of choice is albendazole or if possible, surgical removal of the worm in accessible areas and when the parasite can be located. Prevention is by avoiding all dishes that contain raw or poorly cooked flesh of animals or fish in or imported from endemic areas....

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