- 1 On being a patient
- 2 Modern medicine: foundations, achievements, and limitations
- 3 Global patterns of disease and medical practice
- 4 Cell biology
- 5 Immunological mechanisms
- 6 Principles of clinical oncology
- 7 Infection
- 7.1 Pathogenic microorganisms and the host
- 7.2 The patient with suspected infection
- 7.3 Immunization
- 7.4 Travel and expedition medicine
- 7.5 Viruses
- 7.6 Bacteria
- 7.7 Fungi (mycoses)
- 7.8 Protozoa
- 7.8.1 Amoebic infections
- 7.8.2 Malaria
- 7.8.3 Babesiosis
- 7.8.4 Toxoplasmosis
- 7.8.5 <i>Cryptosporidium</i> and cryptosporidiosis
- 7.8.6 <i>Cyclospora</i> and cyclosporiasis
- 7.8.7 Sarcocystosis (sarcosporidiosis)
- 7.8.8 Giardiasis, balantidiasis, isosporiasis, and microsporidiosis
- 7.8.9 <i>Blastocystis hominis</i> infection
- 7.8.10 Human African trypanosomiasis
- 7.8.11 Chagas disease
- 7.8.12 Leishmaniasis
- 7.8.13 Trichomoniasis
- 7.9 Nematodes (roundworms)
- 7.10 Cestodes (tapeworms)
- 7.11 Trematodes (flukes)
- 7.12 Nonvenomous arthropods
- 7.13 Pentastomiasis (porocephalosis, linguatulosis/linguatuliasis)
- 8 Sexually transmitted diseases and sexual health
- 9 Chemical and physical injuries and environmental factors and disease
- 10 Clinical pharmacology
- 11 Nutrition
- 12 Metabolic disorders
- 13 Endocrine disorders
- 14 Medical disorders in pregnancy
- 15 Gastroenterological disorders
- 16 Cardiovascular disorders
- 17 Critical care medicine
- 18 Respiratory disorders
- 19 Rheumatological disorders
- 20 Disorders of the skeleton
- 21 Disorders of the kidney and urinary tract
- 22 Disorders of the blood
- 23 Disorders of the skin
- 24 Neurological disorders
- 25 The eye
- 26 Psychiatry and drug related problems
- 27 Forensic medicine
- 28 Sports medicine
- 29 Geratology
- 30 Pain
- 31 Palliative medicine
- 32 Biochemistry in medicine
- 33 Acute medicine
David A. Warrell
, Janet Hemingway
, Kevin Marsh
, Robert E. Sinden
, Geoffrey A. Butcher
, and Robert W. Snow
Epidemiology—decreasing global mortality, estimated at 655 000 deaths in 2010, 26% lower than in 2000; mortality in India variously estimated at between 2000 and 277 000.
Parasite biology—new data on merozoite invasion.
Plasmodium ovale—two species distinguished: Plasmodium ovale curtisi (classic) and P. o. wallikeri (variant).
Plasmodium gaboni sp. nov.—found in chimpanzees in Gabon, close to P. falciparum and P. reichenowi and might infect humans.
Plasmodium vivax—increasing evidence of severe infections.
Mosquitoes—increasing pyrethroid kdr resistance and threat to the bed net campaign.
Malaria-induced immunosuppression—malaria causes bacteraemia in sub-Saharan Africa; mechanism of secondary nontyphoid salmonella infections.
Chemotherapy—artemisinin resistance, superiority of artesunate in African children, use of prereferral rectal artesunate.
Vaccine—controversial interim analysis of RTS,S/AS01vaccine phase III trial; volunteer trials of irradiated sporozoite vaccine.
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