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Penicillium marneffei infection 

Penicillium marneffei infection

Chapter:
Penicillium marneffei infection
Author(s):

Thira Sirisanthana

DOI:
10.1093/med/9780199204854.003.070706_update_001

May 30, 2013: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

Update:

Reports of Penicillium marneffei infection in HIV-negative transplant recipients.

Updated on 31 May 2012. The previous version of this content can be found here.
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date: 22 August 2017

Penicillium marneffei infection is very rare in the immunocompetent but one of the most common opportunistic infections in HIV-infected people in South-East Asia, north-eastern India, southern China, Hong Kong, and Taiwan. Presentation is usually with fever, chills, lymphadenopathy, hepatomegaly, and splenomegaly, with skin lesions—most commonly papules with central necrotic umbilication—in two-thirds of cases. Diagnosis is made by microscopy of bone marrow aspirate or biopsy specimens. Standard treatment, which is usually effective, is with amphotericin B followed by itraconazole....

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