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Epstein–Barr virus 

Epstein–Barr virus

Chapter:
Epstein–Barr virus
Author(s):

M.A. Epstein

and A.B. Rickinson

DOI:
10.1093/med/9780199204854.003.070503_update_002

Update:

Diagnosis—RT-PCR as an adjunct to serological tests.

Treatment—possible role of corticosteroids and antivirals in immunocompetent patients with unusually severe symptoms

Updated on 31 May 2012. The previous version of this content can be found here.
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date: 18 August 2017

Epstein–Barr virus (EBV) is a human herpesvirus with a linear double-stranded DNA genome that is carried asymptomatically by most people. Symptomless primary infection is usual in childhood, establishing a lifelong carrier state where the virus persists as a latent infection of circulating B cells. The virus replicates recurrently in oropharyngeal epithelial cells, with consequent shedding of virus in saliva transmitting infection....

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