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The complement system 

The complement system
Chapter:
The complement system
Author(s):

Marina Botto

and Mark J. Walport

DOI:
10.1093/med/9780199204854.003.050102
Page of

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date: 22 October 2017

The complement system consists of over 20 distinct proteins and is an essential component of the innate immune system. It is a major effector mechanism of host defence against infection and inflammatory responses, has an important role in the physiological removal of immune complexes and dying cells, and plays an accessory role in the induction of antibody responses....

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