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Discovery of embryonic stem cells and the concept of regenerative medicine 

Discovery of embryonic stem cells and the concept of regenerative medicine
Chapter:
Discovery of embryonic stem cells and the concept of regenerative medicine
Author(s):

Martin J. Evans

DOI:
10.1093/med/9780199204854.003.0407
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date: 16 December 2017

In this chapter Sir Martin Evans, who was awarded the Nobel Prize for Physiology or Medicine in 2007, describes the identification of stem cells, initially from certain cultured tumour cells (teratocarcinoma cells) and latterly from early mammalian embryos.

The differentiated cells of the adult vertebrate arise from a single fertilized egg and as development proceeds the commitment to differentiation becomes irreversible....

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