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Intracellular signalling 

Intracellular signalling
Chapter:
Intracellular signalling
Author(s):

R. Andres Floto

DOI:
10.1093/med/9780199204854.003.0405
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date: 12 December 2017

This section outlines the general principles of intracellular signalling. Focusing on cell surface receptors, the requirements for effective transmission of information across the plasma membrane are outlined. The principal mechanisms utilized in mammalian signal transduction are described. For each, the pathological consequences of aberrant signalling and means by which pathways can be pharmacologically targeted are described in molecular terms....

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