Antimicrobial Stewardship
Antimicrobial Stewardship
Consultant Microbiologist
Consultant Pharmacist
Consultant Pharmacist
Cite
Abstract
The problem of antimicrobial-resistant organisms and untreatable infections is of global concern. The concept of antimicrobial stewardship has been developing over the last 10 years. The aim of antimicrobial stewardship is to control antimicrobial use in order to reduce the development of resistance, avoid the side effects associated with antimicrobial use, and optimize clinical outcomes. This book provides a very practical approach to antimicrobial stewardship. It’s very much a ‘how to’ guide supported by a review of the available evidence. Section 1 sets the scene and covers the problem of antimicrobial resistance; the problems in the antimicrobial supply line and initiatives to improve the situation; the principles and goals of antimicrobial stewardship; the psychological, social, cultural, and organizational factors in antimicrobial use and prescribing; and how to establish an antimicrobial stewardship programme. Section 2 reviews the components of antimicrobial stewardship: audit and feedback; antimicrobial policies and formularies; antimicrobial restriction; intravenous to oral switch; measuring antimicrobial consumption; measuring and feeding back stewardship; and the use of information technology in antimicrobial stewardship. Section 3 explores special areas in antimicrobial stewardship: antimicrobial pharmacokinetics and pharmacodynamics; intensive care units; paediatrics; surgical prophylaxis; near-patient testing and infection biomarkers; antimicrobial stewardship in the community and long-term care facilities; and finally antimicrobial stewardship in resource-poor communities.
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Front Matter
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Section 1 Setting the scene and starting up
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1
The international and national challenges faced in ensuring prudent use of antibiotics
Susan Hopkins
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2
What are the principles and goals of antimicrobial stewardship?
Fiona Robb andAndrew Seaton
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3
Managing behaviours: social, cultural, and psychological aspects of antibiotic prescribing and use
Esmita Charani andGabriel Birgand
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4
Implementing an antimicrobial stewardship programme
Patrick Doyle
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1
The international and national challenges faced in ensuring prudent use of antibiotics
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Section 2 Components of an antimicrobial stewardship programme
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Section 3 Special areas in antimicrobial stewardship
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9
Pharmacokinetic and pharmacodynamic principles of antimicrobials
Menino Osbert Cotta andJason Roberts
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10
The role of the microbiology laboratory in antimicrobial stewardship
Peter Riley
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11
Antimicrobial stewardship in the immunocompromised patient
Haifa Lyster
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12
Antimicrobial stewardship in the intensive care setting
Jonathan Ball
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13
Surgical prophylaxis
Tamsin Oswald and others
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14
Antimicrobial stewardship in paediatrics
Sanjay Patel andJulia Bielicki
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15
Stewardship in the primary care and long-term care settings
Naomi Fleming
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16
Antifungal stewardship
Laura Whitney andTihana Bicanic
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17
Near-patient testing, infection biomarkers, and rapid diagnostics
Matthew Dryden
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18
Antimicrobial stewardship in a resource-poor setting
Marc Mendelson
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9
Pharmacokinetic and pharmacodynamic principles of antimicrobials
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End Matter
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