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Fatigue, pain, and quality of life 

Fatigue, pain, and quality of life
Chapter:
Fatigue, pain, and quality of life
Author(s):

Roald Omdal

and Katrine Brække Norheim

DOI:
10.1093/med/9780198736950.003.0005
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date: 16 February 2019

Chronic fatigue is one of the most troublesome and debilitating phenomenon that patients with primary Sjögren´s syndrome (pSS) encounter. There are many hypotheses and opinions about fatigue, and there is no consensus on the aetiology, pathogenesis, and treatment. It is therefore important to investigate and try to understand the mechanisms that lead to and regulate fatigue, so that relevant treatment strategies can be developed and implemented. There is no good evidence to suggest that fatigue in pSS is different from fatigue in other diseases and conditions, and this chapter will therefore discuss fatigue as a general phenomenon, with emphasis on pSS where appropriate.

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