Show Summary Details
Page of

Peptide Transporter Defects in Human Leukocyte Antigen Class I Deficiency 

Peptide Transporter Defects in Human Leukocyte Antigen Class I Deficiency
Chapter:
Peptide Transporter Defects in Human Leukocyte Antigen Class I Deficiency
Author(s):

Henri de la Salle

, Lionel Donato

, and Daniel Hanau

DOI:
10.1093/med/9780195389838.003.0017
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2015. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy).

date: 12 December 2017

Primary immunodeficiency diseases are inherited disorders that affect human adaptive and innate immunity. In most cases, affected individuals experience recurrent infections, but they may also suffer from autoimmune diseases and malignancies. This chapter focuses on Peptide Transporter Defects in Human Leukocyte Antigen Class I Deficiency, including the historic and scientific background, clinical presentations, immunologic characteristics, and the molecular/genetic underpinnings. Where appropriate, diagnostic tools and therapeutic options are outlined -- from prophylactic anti-infective measures to hematopoietic stem cell transplantation and gene therapy.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.