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Commentary: Bioethical Considerations in Autism Research and Translation: Present and Future 

Commentary: Bioethical Considerations in Autism Research and Translation: Present and Future
Chapter:
Commentary: Bioethical Considerations in Autism Research and Translation: Present and Future
Author(s):

Holly K. Tabor

DOI:
10.1093/med/9780195371826.003.0087
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date: 10 December 2017

This commentary highlights several key and emerging challenges in autism research and in the shifting boundaries between research and clinical translation, which are likely to influence the practice of clinicians and researchers, as well as the experiences of families, in the near future. The first area examined is the challenge of obtaining meaningful assent for children with autism. While the issue is examined in a research context for children under the age of eighteen years, many of the same issues are applicable for adults with autism because of the communication difficulties associated with the disorder; these are also relevant for informed consent in a clinical context. The second area examined is the research ethics involved with the enrollment of typically developing siblings of children with autism in research. The third area examined is the risk of therapeutic misconception in autism research. The fourth area examined is the potential for challenges associated with accelerated translation of research findings into clinical practice, using the example of array comparative genomic hybridization testing for autism.

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