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Known and Possible Roles of Epigenetics in Autism 

Known and Possible Roles of Epigenetics in Autism
Chapter:
Known and Possible Roles of Epigenetics in Autism
Author(s):

Richard Person

, Xinna Zhang

, Soeun Kim

, Marwan Shinawi

, and Arthur L. Beaudet

DOI:
10.1093/med/9780195371826.003.0048
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date: 23 October 2017

This chapter reviews the known and hypothetical roles of epigenetics in the etiology of autism. It discusses the biochemistry and molecular biology of epigenetic regulation; biology and heritability of epigenetics; epimutations and transgenerational inheritance; methods for epigenetic analysis; difficulties encountered in epigenetic studies of human disease; epigenetics and disease states; epimutations that cause disease; epigenetics and autism, schizophrenia, and related phenotypes; examples of studies of postmortem brain in autism; and the potential for epigenetic therapy.

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