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Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders 

Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders

Chapter:
Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum Disorders
Author(s):

Meera E. Modi

and Larry J. Young

DOI:
10.1093/med/9780195371826.003.0039
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date: 28 April 2017

This chapter examines the role that oxytocin, arginine vasopressin, and their related systems play in mediating the core components of social behavior. It discusses their involvement in both normal social behavior and how their disregulation leads to disturbances in behavior. Parallels are drawn between the neurobiological findings in animal models and the genetic and imaging studies done in both typical and clinical human populations. Finally, the direct evidence implicating a role for these neuropeptide systems in autism spectrum disorders is presented with a discussion of how these findings may shape the development of novel pharmacological therapies for treating social impairment.

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