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A Young Woman with Infertility 

A Young Woman with Infertility
Chapter:
A Young Woman with Infertility
Author(s):

Alexandra Lovett

, and Whitney W. Woodmansee

DOI:
10.1093/med/9780190609917.003.0010
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date: 22 September 2017

Prolactinomas are pituitary adenomas that are prolactin-secreting and can lead to galactorrhea, amenorrhea, and infertility. These symptoms often cause women to present earlier than their male counterparts, who are more likely to develop headaches and visual field deficits. Hyperprolactinemia warrants a thorough workup, which should include pregnancy testing, a thyroid-stimulating hormone level, and a thorough review of the patient’s medications. A pituitary-protocoled magnetic resonance image (MRI) with gadolinium should then be performed to look for an adenoma. Prolactinomas can be watched with surveillance levels and imaging or treated with dopaminergic agonists. Treatment resistance is uncommon, though if it occurs, transsphenoidal resection and/or radiation therapy can be considered.

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