Clinical Medicine

This resource provides information for the management of disorders occurring during sleep and brings greater awareness to the treatment of sleep disorders, as well as treatments of neurological, medical, and psychiatric disorders. ...Less

This resource summarizes the advances in our understanding of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), as well as the potential relationship between the two. ...Less

The Atlas of X-Linked Intellectual Disability Syndromes is a comprehensive summary of the clinically distinctive disorders caused by genes on the X chromosome. Each syndrome is defined and information is provided on somatic features, growth and development, neurological signs, cognitive performance, imaging and other laboratory findings, and when possible, the nature and localization of the responsible gene. Craniofacial and other somatic findings are extensively illustrated. A differential matrix accompanies each syndrome description to assist the reader in identifying other X-linked syndromes with overlapping features. Individual syndrome entries are supplemented with nineteen appendices that identify syndromes with common features and provide the location or mapping limits and function of the responsible genes. ...Less

Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research. Approximately 1 in 100 children are diagnosed as autistic, so it is also an intense growth area in behavioral and educational treatments. Financial resources have begun to be raised for more comprehensive research and an increasing number of scientists are becoming involved in autism research. In many respects, autism has become a model for conducting translational research on a psychiatric disorder. This text provides a summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders including major behavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology. ...Less

This resource demonstrates that autism, like mental retardation, is a clinical presentation of numerous different diseases, many with genomic underpinnings. In this ground-breaking work, the authors explain in great detail how to clinically diagnose infants, children, adolescents and adults with autistic behavioral features and their psychiatric and neurological work-ups. ...Less

This resource provides a framework for understanding the pathophysiology of diseases involving the vestibular system, and is divided into four parts: Anatomy and physiology of the vestibular system; Evaluation of the dizzy patient; Diagnosis and management of common neurotologic disorders; and Symptomatic treatment of vertigo. ...Less

Dysmorphology is the study of congenital malformations and is one of the core areas of clinical genetics. Often the first professional seeing these birth defects is a pediatrician, who notices, for example, that the ears may be rather low set. While in itself minor, this physical sign may indicate a malformation that will be accompanied by other serious genetic disorders. Does the sign, or does it not, indicate an underlying syndrome? The aim of this resource is to provide a practical solution to questions like these. ...Less

Behavioral neurology is founded on lesions of cortical gray matter, but recently the contributions of cerebral white matter to cognitive and emotional dysfunction have also attracted attention. The Behavioral Neurology of White Matter surveys this broad and fascinating field from a clinical perspective. Stimulated by recent improvements in neuroimaging, white matter has been carefully studied, and its role in the operations of cognition and emotion clarified by correlations with clinical observations. ...Less

This resource discusses a neurologic condition that medically and legally defines death, the clinical criteria for brain death, and compresses an amazing amount of scholarship, opinions, and clinical research into one small volume. It aims to present a practical book that can be used at the bedside. It expands on the current criteria used in countries throughout the world and highlights the often inexplicable differences among them. There is also a comprehensive discussion of the new 2010 American Academy of Neurology guidelines on determining brain death. ...Less

The definitive guide to clinical neurology, the twelfth edition of Brain's Diseases of the Nervous System provides detailed coverage of the full range of major neurological conditions, and includes updated sections on genetics, development neurology, and re-written introductory chapters. ...Less