Neurology

This resource provides information for the management of disorders occurring during sleep and brings greater awareness to the treatment of sleep disorders, as well as treatments of neurological, medical, and psychiatric disorders.Less

This new resource is divided into sections based on the major peripheral nerves. It contains detailed illustrations of each nerve along with a discussion of its anatomy, followed by a thorough outline of the clinical conditions and entrapment syndromes that affect the nerve, including a list of the etiologies, clinical features, and electrodiagnostic strategies used for each syndrome. Routine and special motor and sensory nerve conduction studies are shown in an anatomical illustration. In addition, each muscle supplied by the peripheral nerve is illustrated showing the root, plexus, and peripheral nerve supply to the muscle and is accompanied by a corresponding human photograph.Less

Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research, and is now an intense growth area in behavioral and educational treatments. This resource provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders, including major behavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology.Less

This resource demonstrates that autism, like mental retardation, is a clinical presentation of numerous different diseases, many with genomic underpinnings. In this ground-breaking work, the authors explain in great detail how to clinically diagnose infants, children, adolescents and adults with autistic behavioral features and their psychiatric and neurological work-ups.Less

This resource discusses the identification of potential therapeutic targets for autism that can be tested in genetic models and hopefully translated into novel, rational therapies. It provides a roadmap to multitude of relatively rare mutations that have been identified as causes of autism and clarifies what is known at the molecular, cellular, and circuit levels. Focusing on tractable genetic findings in human autism and painstakingly dissecting the underlying neurobiology, this resource aids the understanding of the pathophysiology of autism and ultimately to identifying novel treatments.Less

This new edition of Autonomic Failure features numerous new chapters and makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. It provides a rational guide to aid in the recognition and management of autonomic disorders for practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine.Less

This resource provides a framework for understanding the pathophysiology of diseases involving the vestibular system, and is divided into four parts: Anatomy and physiology of the vestibular system; Evaluation of the dizzy patient; Diagnosis and management of common neurotologic disorders; and Symptomatic treatment of vertigo.Less

The central nervous system consists of gray matter structures, including the neocortex, basal ganglia, thalamus, and cerebellum, and an extensive array of connecting white matter tracts that allow the integration of the many functions mediated by the gray matter. Neuroscience, neurology, and behavioral neurology have tended to emphasize gray matter function and have left white matter disorders and the essential behavioral functions of white matter relatively unexplored. Individual diseases such as multiple sclerosis have been studied extensively, but an integrated view of the function of white matter and patterns of dysfunction occurring when white matter is affected has been lacking. In this resource, the author redresses this imbalance and provides a detailed discussion of the biology of white matter, the phenomenology of white matter diseases, and the pathological disturbances that affect primarily the white matter. The book discusses how great an effect white matter diseases have overall, contributing to many disease processes and providing the neurobiological basis for many cognitive disturbances.Less

Offering a practical approach to the introduction of sleep medicine, this resource uses actual patient cases from the Cleveland Clinic Sleep Disorders Center, and features a wide spectrum of diagnoses to expose the reader to the extensive range of sleep-wake disorders that a patient can experience. Designed to illustrate the signs and symptoms, diagnostic criteria, workup and routine treatment of patients presenting to the sleep clinic, readers will find this a practical source of information.Less

This resource features 60 chapters written by the world's elite clinicians from neurology, geriatrics and research on all aspects of geriatric neurology, and the authors have incorporated the geriatric care perspective and a quality-oriented approach to health care throughout, resulting in the definitive reference for all clinicians caring for older people as well as for those who set policies that affect research and clinical practice.Less

Clinical neurophysiologic testing is an important component of evaluating patients with complaints that may be attributed to diseases of the central or peripheral nervous system. This classic volume in the Contemporary Neurology Series covers the basic concepts underlying each of the testing techniques and provides comprehensive descriptions of the methods and wide range of electrophysiologic testing available for patients with epilepsy, neuromuscular diseases, movement disorders, demyelinating diseases, sleep disorders, autonomic disorders and those undergoing orthopedic and neurosurgical procedures. This text details the role of each study, the interpretation of findings, and their application clinical problems. This text describes the multiple diagnostic procedures for diverse diseases of the neuromuscular system, including: electroencephalography (EEG); electromyography and nerve conduction studies; single fiber EMG; polysomnography; surface EMG patterns, blood pressure, pulse, sweat measures; vestibular function testing; deep brain stimulator physiology; and intraoperative monitoring. It is a practical textbook for neurologists, physiatrists and clinical neurophysiologists in clinical or research practice or in training. Key features of the new edition include fully updated chapters to reflect new research and techniques in clinical neurophysiology; updated images illustrating key elements of techniques and basic concepts; case examples for practical application. Less

Dr. Kimura has built upon his extensive experience teaching electromyography (EMG) around the world and has transferred his knowledge to this resource, which is intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination. It covers noninvasive electrodiagnostic methods, particularly electromyography (EMG). This resource provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test.Less

This resource applies a case-based approach of consultation, and presents 31 actual cases that provide key points to remember, as well as recommendations for further reading at the end of each case. It also includes EEGs and imaging where applicable.Less

This resource offers comprehensive instruction on the diagnosis and treatment of all varieties of eye movement disorders, and reflects the importance of correlating clinical signs of disorders in the oculomotor system with their neuroanatomic and neurophysiologic architecture. With its focus on signs and symptoms, it advances lesion localization of eye movement disorders as the central clinical concern, and presents a fresh review of bedside examination techniques in the ER, ICU, and walk-in clinic; productive ways of taking a clinical history; sign interpretation; source lesion localization; and, where appropriate, therapy. This resource is arranged according to objective signs - like ptosis, neuromuscular syndromes, dizziness, vertigo, and syndromes of the medulla - rather than disease entities, and features over 50 clinical cases, each one providing the anatomical guidance needed to make critical diagnostic and management decisions in patients who often present with abnormal eye movements.Less

This resource presents a representative set of 33 ‘mini-cases’ of headache and facial pain, and is divided into three sections that cover the typical ground for head/face pain consultation: (1) Diagnostic Questions, (2) Treatment Considerations, and (3) Prognostic, Social and Legal Issues. Recommendations are based on the most current evidence available, and diagnostic thinking is presented along the lines of the International Classification of Headache Disorders, second edition (ICHD-II).Less

This resource brings the theme of a global campaign to the forefront. Researchers, scientists, and respected clinicians from around the world discuss aspects of access to care, individual and societal burden. Less

This resource, considered the 'bible' of basic epilepsy research, offers encyclopedic coverage and in depth discussions of leading research hypotheses and strategic approaches. Indispensable for students and all research scientists in the field of epilepsy research, and now of practical importance to the clinic, it also maps out new research directions for the next decade.Less

Huntington's disease (HD) is an inherited progressive neurodegenerative disorder. Although onset of HD usually occurs in adulthood, a small percentage of cases develop symptoms before 20 years of age (juvenile-onset Huntington's Disease or JHD). This resource summarises the clinical and scientific knowledge available on JHD. Less

This textbook guides the medical student, regardless of background or intended specialty, through the anatomy and function of the human nervous system. In writing specifically for medical students, the author concentrates on the neural contributions to common diseases, whether neurological or not, and omits topics without clinical relevance. The two fundamental building blocks of the nervous system are neural communication and neuroanatomy. Foundations in both topics must be mastered. After learning the neurons and glial cells that comprise the nervous system, the book begins with a study of the anatomy of the nervous system before moving on to neural communication. With these basics of neurophysiology and neuroanatomy in hand, the reader is ready to tackle how the brain “works” by examining perception, voluntary movement, and homeostasis. The book is intended as a “travel guide” to the human brain, one that communicates to the reader the profound power and beauty of brain function while providing a memorable and enjoyable trip.Less

This resource addresses the increasingly sophisticated neuroimaging techniques that have allowed researchers to begin to define functional and anatomical characteristics of migraine and other less-common types of headache. Of particular focus is how imaging is changing the way we understand migraine. This includes changes in function, structure and chemistry of the migraine brain. Included are sections that focus on particular aspects of migraine, including aura, sensory difficulty, slurred language, and motor dysfunction. It also includes a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG), and details on modulation of the brain using such techniques as TMS. Less